After administering a Ceftriaxone Injection, monitor patients for allergic reactions such as rash, swelling, or difficulty breathing. Observe for signs of anaphylaxis, including hypotension and tachycardia. Assess injection site for pain, redness, or swelling. Monitor renal and hepatic function, especially in long-term use. Check for gastrointestinal symptoms like diarrhea, which may indicate Ceftriaxone Injection associated Clostridium difficile infection. Watch for neurological effects such as seizures in patients with renal impairment. Regularly evaluate blood counts to detect possible hematologic reactions. If severe reactions occur, discontinue Ceftriaxone Injection and provide appropriate medical intervention immediately.